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Home Antibody All anti-IRF9 antibodies

Anti-IRF9 Antibody EPR3939

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307828
  • Rabbit monoclonal antibody against IRF9(clone EPR3939)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401832) , 20ug
100ul 325 In Stock
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WB(1)
FC(1)
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Also for IRF9 (NM_006084)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IRF9 was used as an immunogen.
Clone NameEPR3939 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, FC Suggested DilutionsICC: 1:100 - 1:250; WB: 1:10000 - 1:50000; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens interferon regulatory factor 9 (IRF9)
Alternative NameIRF-9; ISGF3; ISGF3G; p48
Database LinkNP_006075
FunctionIRF9, or Interferon regulatory factor 9, is a transcription regulatory factor that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STAT’s then dimerize, associate with IRF9/ISGF3G to form a complex called ISGF3 transcription factor, which enters the nucleus. Moreover, IRF9 is translocated into the nucleus upon activation by IFN-alpha/beta (1).
Related Pathway
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - TF IRF9 antibody [EPR3939]; All lanes : Anti-Interferon regulatory factor 9 antibody [EPR3939] at 1/1000 dilution.Lane 1 : K562 treated with IFN-alpha cell lysates.Lane 2 : K562 cell lysates.Lane 3 : HeLa treated with IFN-alpha cell lysates.Lane 4 : HeLa cell lysates.Lane 5 : Jurkat cell lysates.Lysates/proteins at 10 ug per lane.Predicted band size : 44 kDa.Observed band size : 48 kDa .
FC Image
Flow Cytometry - TF IRF9 antibody [EPR3939]; Flow cytometric analysis of permeabilized Jurkat cells using TA307828 at 1/10 dilution (red)and Rabbit IgG negative control (green).

 

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