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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]
Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]
Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]
Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]
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 Home All anti-IRF6 antibodies

Anti-IRF6 TrueMAB Antibody Clone 2C10

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA503159
  • Purified IRF6 mouse monoclonal antibody,clone 2C10
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401852) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF503159
  • Carrier-free (BSA/glycerol-free) IRF6 mouse monoclonal antibody,clone 2C10
100ug $450 3-4 weeks Add to Shopping Cart
WB(2)
IHC(10)
IF(1)
FC(1)
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Also for IRF6 (NM_006147)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens interferon regulatory factor 6 (IRF6), transcript variant 1
Synonyms:LPS; OFC6; PIT; PPS; PPS1; VWS; VWS1
ImmunogenFull length human recombinant protein of human IRF6(NP_006138) produced in HEK293T cell.
BufferPBS (PH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone NameClone 2C10 IsotypeIgG1
Species ReactivityHuman , Dog , Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF, FC Suggested DilutionsWB 1:500~2000, IHC 1:150, IF 1:100, FLOW 1:100,
BackgroundThis gene encodes a member of the interferon regulatory transcription factor (IRF) family. Family members share a highly-conserved N-terminal helix-turn-helix DNA-binding domain and a less conserved C-terminal protein-binding domain. The encoded protein may be a transcriptional activator. Mutations in this gene can cause van der Woude syndrome and popliteal pterygium syndrome. Mutations in this gene are also associated with non-syndromic orofacial cleft type 6. Alternate splicing results in multiple transcript variants.
Related Pathway
Apoptosis

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY IRF6 (RC201579, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-IRF6.
WB Image
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-IRF6 monoclonal antibody.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Human colon tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human endometrium tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Human prostate tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-IRF6 mouse monoclonal antibody. (TA503159)
IHC Image
Immunohistochemical staining of paraffin-embedded Human tonsil using anti-IRF6 mouse monoclonal antibody. (TA503159)
IF Image
Anti-IRF6 mouse monoclonal antibody (TA503159) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY IRF6(RC201579).
FC Image
HEK293T cells transfected with either RC201579 overexpress plasmid(Red) or empty vector control plasmid(Blue) were immunostained by anti-IRF6 antibody(TA503159), and then analyzed by flow cytometry.

 

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