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Home Antibody All anti-IRAK4 antibodies

Anti-IRAK4 Antibody

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SKU Description Amount Price Availability*  
TA302664 Goat Polyclonal Antibody against IRAK4 (N Terminus) 100ug $325 3-7 Days
LC402503 IRAK4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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OriGene Data

Immunogen Peptide with sequence NKPITPSTYVRC, from the N Terminus of the protein sequence according to NP_057207.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse. Expected from seq similarity: Human, Mouse Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 1-3µg/ml.
Predicted MW Explanation 51.3 kDa
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens interleukin-1 receptor-associated kinase 4 (IRAK4), transcript variant 2
Alternative NameIPD1; IRAK-4; NY-REN-64; REN64
Database LinkNP_057207
Entrez Gene 51135 Human
Entrez Gene 266632 Mouse
FunctionThis gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene. [supplied by RefSeq].
Related PathwayProtein KinaseDruggable Genome ApoptosisToll-like receptor signaling pathwayNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA302664 (1µg/ml) staining of Hela lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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