Home Antibody All anti-INPP5B antibodies
Also for INPP5B (NM_005540)
|Recombinant fragment corresponding to a region within amino acids 699 and 949 of INPP5B (Uniprot ID#P32019)|
|Human (Predicted: Mouse, Rat)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Mouse (87%), Rat (87%)
|Homo sapiens inositol polyphosphate-5-phosphatase, 75kDa (INPP5B), transcript variant 1|
Entrez Gene 3633 Human
Entrez Gene 16330 Mouse
Entrez Gene 362590 Rat
|Cellular calcium signaling is controlled by the production of inositol phosphates (IPs) by phospholipase C in response to extracellular signals. The IP signaling molecules are inactivated by a family of inositol polyphosphate-5-phosphatases (5-phosphatases). This gene encodes the type II 5-phosphatase. The protein is localized to the cytosol and mitochondria, and associates with membranes through an isoprenyl modification near the C-terminus. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq]|
|Druggable Genome Inositol phosphate metabolismMetabolic pathwaysPhosphatidylinositol signaling system|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
Sample (30 ug of whole cell lysate). A: H1299. 7.5% SDS PAGE. TA308024 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded Ca922 xenograft, using INPP5B(TA308024) antibody at 1:100 dilution.