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Home Antibody All anti-IL8 antibodies

Anti-IL8 Antibody EPR1116(2)


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307871 Rabbit monoclonal antibody against IL-8(clone EPR1116(2)) 100ul $325 In Stock
LC400198 CXCL8 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human IL-8 was used as an immunogen.
Clone NameEPR1116(2) IsotypeIgG
Species ReactivityMouse, Human (Does not react with: Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens chemokine (C-X-C motif) ligand 8 (CXCL8)
Database LinkNP_000575
Entrez Gene 3576 Human
FunctionChemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors (1). Interleukin-8 (IL-8) belongs to a family of small, structurally related cytokines similar to platelet factor 4. It is produced by phagocytes and mesenchymal cells exposed to inflammatory stimuli (e.g., interleukin-1 or tumor necrosis factor) and activates neutrophils inducing chemotaxis, exocytosis and the respiratory burst. In vivo, IL-8 elicits a massive neutrophil accumulation at the site of injection (2). It has recently been shown that IL-8, through its effects on the macrophage and endothelial cell, may be involved in the pathogenesis of atherosclerosis (3).
Related PathwaySecreted ProteinTransmembraneDruggable Genome Cytokine-cytokine receptor interactionChemokine signaling pathwayToll-like receptor signaling pathwayNOD-like receptor signaling pathwayRIG-I-like receptor signaling pathwayEpithelial cell signaling in Helicobacter pylori infectionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - IL8 antibody [EPR1116(2)]; Anti-IL8 antibody [EPR1116(2)] at 1/1000 dilution + IL8 recombinant protein at 10 ug.Predicted band size : 11 kDa.


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