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Home Antibody All anti-IL6 antibodies

Anti-IL6 Antibody E457


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA300413 Rabbit Monoclonal Antibody against IL6 (Clone E457) 100ul $325 In Stock
LC424617 IL6 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA recombinant human IL-6 protein was used as immunogen.
Clone NameE457 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:10000
Predicted MW Explanation 24 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens interleukin 6 (IL6)
Alternative NameBSF2; HGF; HSF; IFNB2; IL-6
Database LinkNP_000591
Entrez Gene 3569 Human
FunctionInterleukin-6 (IL-6) is a multifunctional cytokine with a wide variety of biological functions. IL-6 is implicated in the final differentiation of B-cells into immunoglobulin-secreting cells (1), myeloma and plasmacytoma growth (2), nerve cell differentiation, and activation of hepatocytes and mitogen-stimulated helper T cells (3). Upon activation, IL-6 induces at least three major signaling pathways: JAK/STAT, PI-3 kinase and MAPK (4,5).
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionToll-like receptor signaling pathwayNOD-like receptor signaling pathwayCytosolic DNA-sensing pathwayJak-STAT signaling pathwayHematopoietic cell lineageMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - IL6 antibody [E457]; Anti-IL6 antibody [E457].Predicted band size : 24 kDa.Observed band size : 22 kDa .

WB Image
Western blot - IL6 antibody [E457]; Anti-IL6 antibody [E457] at 1/1000 dilution + Media from cultured human prostate tissue at 30 ug.Secondary.An HRP-conjugated anti-rabbit IgG polyclonal (1/1000).Predicted band size : 24 kDa.Observed band size : 24 kDa.Additional bands at : 30 kDa. We are unsure as to the identity of these extra bands.This image is courtesy of an anonymous customer.


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