OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-IL5RA antibodies

Anti-IL5RA Antibody EPR5450(2)

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310626
  • Rabbit Monoclonal antibody against IL-5R alpha (IL5RA)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC425002) , 20ug
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human IL-5R alpha was used as an immunogen.
Clone NameEPR5450(2) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC-P or IP.
Purification Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens interleukin 5 receptor, alpha (IL5RA), transcript variant 1
Alternative NameCD125; CDw125; HSIL5R3; IL5R
Database LinkNP_000555
FunctionIL-5R alpha is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. IL-5R alpha has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4 (1).
Related Pathway
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-IL5RA antibody [EPR5450(2)]; All lanes : Anti-IL5RA antibody [EPR5450(2)] at 1/1000 dilution.Lane 1 : Human platelet lysate.Lane 2 : Human serum lysate.Lysates/proteins at 10 ug per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 48 kDa.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title