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Anti-IL5RA Antibody EPR5450(2)
Also for IL5RA (NM_000564)
|A synthetic peptide corresponding to residues near the C-terminus of human IL-5R alpha was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for IHC-P or IP.|
|Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for IHC-P or IP.
|Homo sapiens interleukin 5 receptor, alpha (IL5RA), transcript variant 1|
|CD125; CDw125; HSIL5R3; IL5R|
|IL-5R alpha is an interleukin 5 specific subunit of a heterodimeric cytokine receptor. The receptor is comprised of a ligand specific alpha subunit and a signal transducing beta subunit shared by the receptors for interleukin 3 (IL3), colony stimulating factor 2 (CSF2/GM-CSF), and interleukin 5 (IL5). The binding of this protein to IL5 depends on the beta subunit. The beta subunit is activated by the ligand binding, and is required for the biological activities of IL5. IL-5R alpha has been found to interact with syndecan binding protein (syntenin), which is required for IL5 mediated activation of the transcription factor SOX4 (1). |
Cytokine-cytokine receptor interaction
Hematopoietic cell lineage
Jak-STAT signaling pathway
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Western blot - Anti-IL5RA antibody [EPR5450(2)]; All lanes : Anti-IL5RA antibody [EPR5450(2)] at 1/1000 dilution.Lane 1 : Human platelet lysate.Lane 2 : Human serum lysate.Lysates/proteins at 10 µg per lane.Secondary.Standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 48 kDa.