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Home Antibody All anti-IL32 antibodies

Anti-IL32 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306297
  • Rabbit Polyclonal IL-32 Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC422884) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for IL32 (NM_001012631)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenIL-32 antibody was raised against a 16 amino acid peptide from near the center of human IL-32.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 2.5 - 5 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 32 (IL32), transcript variant 1
Alternative NameIL-32alpha; IL-32beta; IL-32delta; IL-32gamma; NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd
Database LinkNP_001012649
FunctionInterleukin-32 (IL-32) was initially identified as a transcript (NK4) that is selectively expressed in lymphocytes and NK cells and whose expression is increased following activation by IL-2 . It was later re-isolated from an IL-18-treated lung carcinoma cell line and re-named IL-32 (2). IL-32 is unusual in that it does not share sequence homology with known cytokine families and is highly expressed in immune tissues, existing in at least four differentially spliced isoforms. Because treatment of human monocytic and mouse macrophage cells with IL-32 induces several proinflammatory cytokines such as TNF-alpha, IL-8 and MIP-2, and because it is also induced in human peripheral lymphocyte cells after mitogen stimulation and in epithelial cells by IFNgamma, it has been suggested that IL-32 may play a role in autoimmune and inflammatory diseases such as rheumatoid arthritis (3).
Related Pathway

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WB Image
Western blot analysis of IL-32 in Jurkat cell lysate with IL-32 antibody at (A) 2.5 and (B) 5 µg/ml.

 

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