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Home Antibody All anti-IL27RA antibodies

Anti-IL27RA Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306080
  • Rabbit Polyclonal TCCR Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC417709) , 20ug
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for IL27RA (NM_004843)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenTCCR antibody was raised against a synthetic peptide corresponding to amino acids near the amino terminus of human TCCR precursor.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens interleukin 27 receptor, alpha (IL27RA)
Alternative NameCRL1; IL-27RA; IL27R; TCCR; WSX1; zcytor1
Database LinkNP_004834
FunctionUpon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-gamma and lymphotoxin-beta that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned (1,2). It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1 (1,2). TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-gamma and Th1-dependent antibody IgG2a . TCCR is predominately expressed in thymus, spleen, lymph notes and peripheral blood leukocytes.
Related Pathway

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WB Image
Western blot analysis of TCCR expression in human spleen tissue lysates with TCCR antibody at 1 ug /ml.
IHC Image
Immunohistochemistry of TCCR in human spleen tissue with TCCR antibody at 10 ug/ml.

 

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