Home Antibody All anti-IL21R antibodies
Also for IL21R (NM_021798)
|IL-21 receptor antibody was raised against a synthetic peptide corresponding to amino acids 97 to 111 of human IL-21 receptor precursor .|
|Human, Mouse, Rat
||WB: 0.5 - 1 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column
|Homo sapiens interleukin 21 receptor (IL21R), transcript variant 1|
Entrez Gene 50615 Human
Entrez Gene 60504 Mouse
Entrez Gene 308977 Rat
|A novel cytokine related to IL-2 and IL-15 was recently identified and designated IL-21 . The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family (1,2). IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling (3,4). Both IL-21R and the gc are necessary for the IL-21 function. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.|
|TransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway|
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Western blot analysis of IL-21 receptor expression in human Raji cell lysate with IL-21 Receptor antibody at 1 ug /ml.
Immunohistochemistry of IL-21R in rat lung with IL-21R antibody at 10 ug/ml.