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Anti-IL15RA Antibody Polyclonal
Also for IL15RA (NM_172200)
|Rabbit polyclonal IL-15RA antibody was raised against a 16 amino acid peptide near the center of human IL-15RA.|
|Human, Mouse, Rat
||ELISA, WB: 1 - 2 ug/ml
|IL-15RA Antibody is supplied in PBS containing 0.02% sodium azide.|
|IL-15RA Antibody is affinity chromatography purified via peptide column.
|Homo sapiens interleukin 15 receptor, alpha (IL15RA), transcript variant 2|
|IL-15RA Antibody: Interleukin 15 (IL-15RA) is a cytokine receptor that specifically binds IL-15 with high affinity. IL-15 regulates T and natural killer cell activation and proliferation. The IL-15 and IL-2 receptors share two subunits, IL-2R beta and IL-2R gamma, and IL-15RA is structurally related to IL-2RA, an additional IL-2-specific alpha subunit necessary for high affinity IL-2 binding. Unlike IL-2RA, IL-15RA is capable of binding IL-15 with high affinity independent of the other subunits. IL-15RA is thought to enhance cell proliferation and expression of apoptosis inhibitor Bcl-xL and Bcl-2.|
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
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Western blot analysis of IL-15RA in human small intestine tissue lysate with IL-15RA antibody at (A) 1 and (B) 2 ug/mL