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Anti-IL13 Antibody EPR3267
Also for IL13 (NM_002188)
|A synthetic peptide corresponding to residues in human IL-13 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||ICC/IF: 1:50 - 1:100; WB: 1:1000 - 1:5000
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,IHC-P or IP.
|Homo sapiens interleukin 13 (IL13)|
|Interleukin 13 (IL-13) is a cytokine that is produced by T helper type 2 (Th2) cells, mast cells, and basophils (1). It is a major stimulator of inflammation and tissue remodeling at sites of Th2 inflammation (2). IL-13 shares several biological profiles with IL-14, including IgE production, CD23 and MHC Class II expression, inhibition of antibody-dependent cell-mediated cytotoxicity with down regulation of IgG type I receptor, and suppression of type I interferon (3). Also, like IL-4, IL-13 has been genetically and functionally implicated in the pathogenesis of allergy and asthma (4).|
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
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Western blot - Anti-IL13 antibody [EPR3267]; Anti-IL13 antibody [EPR3267] at 1/1000 dilution + Recombinant IL13 protein at 0.05 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 15 kDa.