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Home Antibody All anti-IL12RB1 antibodies

Anti-IL12RB1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308386 Rabbit polyclonal antibody to IL-12R beta1(CD212) (interleukin 12 receptor, beta 1) 100ul $325 3-7 Days
LC417240 IL12RB1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(1)
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Also for IL12RB1 (NM_005535)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 57 and 488 of IL12 Receptor beta1 (Uniprot ID#P42701)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 73kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens interleukin 12 receptor, beta 1 (IL12RB1), transcript variant 1
Alternative NameCD212; IL-12R-BETA1; IL12RB; IMD30
Database LinkNP_005526
Entrez Gene 3594 Human
FunctionThe protein encoded by this gene is a type I transmembrane protein that belongs to the hemopoietin receptor superfamily. This protein binds to interleukine 12 (IL12) with a low affinity, and is thought to be a part of IL12 receptor complex. This protein forms a disulfide-linked oligomer, which is required for its IL12 binding activity. The coexpression of this and IL12RB2 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The lack of expression of this gene was found to result in the immunodeficiency of patients with severe mycobacterial and Salmonella infections. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample(30 ug whole cell lysate). A:A431. 7.5% SDS PAGE. TA308386 diluted at 1:1000
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