OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-IL12A antibodies

Anti-IL12A Antibody EP5737

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310616
  • Rabbit Monoclonal antibody against IL-12 alpha (IL12A)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC431035) , 20ug
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)
spacer
Also for IL12A (NM_000882)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus of human IL-12 alpha was used as an immunogen.
Clone NameEP5737 IsotypeTissue culture supernatant
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500
BufferDoes not react with Rat. Is unsuitable for ICC or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for ICC or IP.

Reference Data

Target NameHomo sapiens interleukin 12A (IL12A)
Alternative NameCLMF; IL-12A; NFSK; NKSF1; P35
Database LinkNP_000873
FunctionIL-12 alpha is a subunit of a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The cytokine is a disulfide-linked heterodimer composed of the 35-kD subunit protein (IL-12 alpha), and a 40-kD subunit (IL-12 beta) that is a member of the cytokine receptor family. This cytokine is required for the T-cell-independent induction of interferon (IFN)-gamma, and is important for the differentiation of both Th1 and Th2 cells. The responses of lymphocytes to this cytokine are mediated by the activator of transcription protein STAT4. Nitric oxide synthase 2A (NOS2A/NOS2) is found to be required for the signaling process of this cytokine in innate immunity (1).
Related Pathway
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
Toll-like receptor signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-IL12A antibody [EP5737]; All lanes : Anti-IL12A antibody [EP5737] at 1/1000 dilution.Lane 1 : NIH3T3 cell lysate.Lane 2 : HuT-78 cell lysate.Lane 3 : Raw 264.7 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 25 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-IL12A antibody [EP5737]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling IL12A with TA310616 antibody at 1/250 dilution.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title