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Home Antibody All anti-IDH2 antibodies

Anti-IDH2 Antibody Polyclonal

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA319664 Rabbit Polyclonal IDH2 Antibody 100ug $325 2 Weeks
LC400787 IDH2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenIDH2 antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human IDH2.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 - 2 ug/ml, IHC: 5 ug/ml, IF: 20 ug/ml
BufferIDH2 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification IDH2 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens isocitrate dehydrogenase 2 (NADP+), mitochondrial (IDH2), transcript variant 1
Alternative NameD2HGA2; ICD-M; IDH; IDHM; IDP; IDPM; mNADP-IDH
Database LinkNP_002159
Entrez Gene 3418 Human
Entrez Gene 269951 Mouse
Entrez Gene 361596 Rat
FunctionIDH2 Antibody: Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Two NADP(+)-dependent isocitrate dehydrogenases have been found as homodimer: IDH1 is predominantly cytosolic and peroxisomal and IDH2 is mitochondrial. Both IDH1 and IDH2 play significant roles in the tricarboxylic acid cycle (TCA), and defects in IDH1 as well as IDH2 have been implicated in the development of glioma as well as other malignancies.
Related Pathway Citrate cycle (TCA cycle)Glutathione metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of IDH2 in human heart tissue lysate with IDH2 antibody at (A) 1 and (B) 2 ug/mL.
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Immunohistochemistry of IDH2 in mouse heart tissue with IDH2 antibody at 5 ug/mL.
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Immunofluorescence of IDH2 in mouse heart tissue with IDH2 antibody at 20 ug/mL.
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