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Home Antibody All anti-ID3 antibodies

Anti-ID3 TRUEMAB Antibody Clone OTI7B6

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA500811 anti-ID3 mouse monoclonal antibody, clone OTI7B6 (formerly 7B6) 100ul $325 In Stock
LC419492 ID3 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
CF500811 Carrier-free (BSA/glycerol-free) ID3 mouse monoclonal antibody, clone OTI7B6 (formerly 7B6) 100ug $450 3-4 weeks
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WB(1)
IHC(1)
IF(3)

OriGene Data

ImmunogenFull length human recombinant protein of human ID3 (NP_002158) produced in HEK293T cell.
Clone NameClone OTI7B6 IsotypeIgG1
Species ReactivityHuman Concentration0.75 mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:2000, IHC 1:50, IF 1:100,
Predicted MW Explanation 13.0 kDa
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Purification Purified from mouse ascites fluids by affinity chromatography

Reference Data

Target NameHomo sapiens inhibitor of DNA binding 3, dominant negative helix-loop-helix protein (ID3)
Alternative NamebHLHb25; HEIR-1
Database LinkNP_002158
Entrez Gene 3399 Human
FunctionThis gene encodes a protein belonging to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in this gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, malignant melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.
Related PathwayES Cell Differentiation/IPSTranscription FactorsDruggable Genome TGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY ID3 (RC200583, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-ID3.
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Immunohistochemical staining of paraffin-embedded Kidney tissue within the normal limits using anti-ID3mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500811, Dilution 1:50)
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Anti-ID3 mouse monoclonal antibody (TA500811) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY ID3(RC200583).
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Immunofluorescent staining of HeLa cells using anti-ID3 mouse monoclonal antibody (TA500811).
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Immunofluorescent staining of HT29 cells using anti-ID3 mouse monoclonal antibody (TA500811).
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