OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-HTR2C antibodies

Anti-HTR2C Antibody EPR6486

div

Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA310599
  • Rabbit Monoclonal antibody against HTR2C
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424472) , 20ug Explanation
100ul $325 3-7 Days
Add to Shopping Cart
spacer
WB(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HTR2C was used as an immunogen.
Clone NameEPR6486 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
BufferpH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA
Note Is unsuitable for Flow Cyt,ICC/IF,IHC-P or IP.

Reference Data

Target NameHomo sapiens 5-hydroxytryptamine (serotonin) receptor 2C, G protein-coupled (HTR2C), transcript variant 2
Alternative Name5-HT1C; 5-HT2C; 5-HTR2C; 5HTR2C; HTR1C
Database LinkNP_000859
Entrez Gene 3358 Human
FunctionSerotonin (5-hydroxytryptamine, 5-HT), a neurotransmitter, elicits a wide array of physiological effects by binding to several receptor subtypes, including the 5-HT2 family of seven-transmembrane-spanning, G-protein-coupled receptors, which activate phospholipase C and D signaling pathways. HTR2C is the 2C subtype of serotonin receptor. Its isoforms differ in their ability to interact with G proteins and the activation of phospholipase C and D signaling cascades, thus modulating serotonergic neurotransmission in the central nervous system. Studies in humans have reported abnormalities in HTR2C in depressed suicide victims (1).
Related PathwayGPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionGap junction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - Anti-5HT2C Receptor antibody [EPR6486]; All lanes : Anti-5HT2C Receptor antibody [EPR6486] at 1/1000 dilution.Lane 1 : SH-SY5Y cell lysate.Lane 2 : A431 cell lysate.Lane 3 : BxPC-3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.standard HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 52 kDa.
spacer
Other-Anti-5HT2C Receptor antibody [EPR6486](TA310599); Equilibrium disassociation constant (KD)..
spacer

 

spacer
Inc 5000 Healthcare Company
All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title