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Anti-HSPA5 Antibody EPR4041(2)
Also for HSPA5 (NM_005347)
|A synthetic peptide corresponding to residues in human GRP78 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant (Protein A or G Sepharose)
|Homo sapiens heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5)|
|BIP; GRP78; MIF2|
|GRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell (1).|
MAPK signaling pathway
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Western blot - GRP78 BiP antibody [EPR4041(2)]; All lanes : Anti-GRP78 BiP antibody [EPR4041(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysates.Lane 2 : NIH/3T3 cell lysates.Lane 3 : LnCaP cell lysates.Lane 4 : HepG2 cell lysates.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 72 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GRP78 BiP antibody [EPR4041(2)]; ab108615 at 1/50 dilution staining GRP78 BiP in Human breast carcinoma tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.