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Home Antibody All anti-HSPA5 antibodies

Anti-HSPA5 Antibody EPR4041(2)

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA307227 Rabbit monoclonal antibody against GRP78(clone EPR4041(2)) 100ul $325 In Stock
LC417364 HSPA5 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for HSPA5 (NM_005347)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GRP78 was used as an immunogen.
Clone NameEPR4041(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
Predicted MW Explanation 72 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5)
Alternative NameBIP; GRP78; HEL-S-89n; MIF2
Database LinkNP_005338
Entrez Gene 3309 Human
Entrez Gene 14828 Mouse
Entrez Gene 25617 Rat
FunctionGRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell (1).
Related PathwayDruggable Genome Antigen processing and presentationPrion diseases

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - GRP78 BiP antibody [EPR4041(2)]; All lanes : Anti-GRP78 BiP antibody [EPR4041(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysates.Lane 2 : NIH/3T3 cell lysates.Lane 3 : LnCaP cell lysates.Lane 4 : HepG2 cell lysates.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 72 kDa.
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Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GRP78 BiP antibody [EPR4041(2)]; TA307227 at 1/50 dilution staining GRP78 BiP in Human breast carcinoma tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.
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