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Home Antibody All anti-HSPA5 antibodies

Anti-HSPA5 Antibody EPR4041(2)

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SKU Description Amount Price Availability*  
TA307227
  • Rabbit monoclonal antibody against GRP78(clone EPR4041(2))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417364) , 20ug Explanation
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for HSPA5 (NM_005347)
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GRP78 was used as an immunogen.
Clone NameEPR4041(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100; ICC: 1:50 - 1:100
Predicted MW Explanation 72 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) (HSPA5)
Alternative NameBIP; GRP78; HEL-S-89n; MIF2
Database LinkNP_005338
Entrez Gene 3309 Human
Entrez Gene 14828 Mouse
Entrez Gene 25617 Rat
FunctionGRP78 (HSPA5), also referred to as 'immunoglobulin heavy chain-binding protein' (BiP), is a member of the heat-shock protein-70 (HSP70) family and is involved in the folding and assembly of proteins in the endoplasmic reticulum (ER). Because so many ER proteins interact transiently with GRP78, it may play a key role in monitoring protein transport through the cell (1).
Related PathwayDruggable Genome Antigen processing and presentationPrion diseases

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - GRP78 BiP antibody [EPR4041(2)]; All lanes : Anti-GRP78 BiP antibody [EPR4041(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysates.Lane 2 : NIH/3T3 cell lysates.Lane 3 : LnCaP cell lysates.Lane 4 : HepG2 cell lysates.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 72 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GRP78 BiP antibody [EPR4041(2)]; TA307227 at 1/50 dilution staining GRP78 BiP in Human breast carcinoma tissue by Immunohistochemistry Formalin-fixed, Paraffin-embedded tissue.

 

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