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Anti-HSD17B10 TRUEMAB Antibody Clone OTI5E2
TrueMAB Antibodies - Made against Authentic Protein Antigens
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Also for HSD17B10 (NM_004493)
|Full length human recombinant protein of human HSD17B10 (NP_004484) produced in HEK293T cell.|
|WB, IHC, IF, FC
||WB 1:2000, IHC 1:50, IF 1:100, Flow 1:100
|PBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.|
|Purified from mouse ascites fluids by affinity chromatography
|Homo sapiens hydroxysteroid (17-beta) dehydrogenase 10 (HSD17B10), transcript variant 1|
|17b-HSD10; ABAD; CAMR; DUPXp11.22; ERAB; HADH2; HCD2; MHBD; MRPP2; MRX17; MRX31; MRXS10; SCHAD|
Entrez Gene 3028 Human
Entrez Gene 700018 Monkey
|This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. |
|Druggable Genome Valine, leucine and isoleucine degradationMetabolic pathwaysAlzheimer's disease|
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HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY HSD17B10 (RC201734, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HSD17B10.
Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-HSD17B10 monoclonal antibody.
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of breast tissue using anti-HSD17B10 mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500813, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded liver tissue within the normal limits using anti-HSD17B10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500813, Dilution 1:50)
Immunohistochemical staining of paraffin-embedded Carcinoma of liver tissue using anti-HSD17B10mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min, TA500813, Dilution 1:50)
Anti-HSD17B10 mouse monoclonal antibody (TA500813) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY HSD17B10(RC201734).
Flow cytometric analysis of Hela cells, using anti-HSD17B10 antibody(TA500813),(Red) compared to a nonspecific negative control antibody(TA50011)(Blue).