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Home Antibody All anti-HSD11B1 antibodies

Anti-HSD11B1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308504
  • Rabbit polyclonal antibody to HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC405624) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for HSD11B1 (NM_181755)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 232 and 292 of HSD11B1
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 32kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 2
Alternative Name11-beta-HSD1; 11-DH; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1
Database LinkNP_861420
Entrez Gene 3290 Human
FunctionThe protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome C21-Steroid hormone metabolismAndrogen and estrogen metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: Hep G2 . 12% SDS PAGE. TA308504 diluted at 1:1000.
IHC Image
HSD11B1 antibody detects HSD11B1 protein at cytosol on hepatoma by immunohistochemical analysis. Sample: Paraffin-embedded hepatoma. HSD11B1 antibody (TA308504) dilution: 1:500.
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HSD11B1(TA308504) antibody at 1:200 dilution.

 

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