Home Antibody All anti-HSD11B1 antibodies
Also for HSD11B1 (NM_181755)
|Synthetic peptide contain a sequence corresponding to a region within amino acids 232 and 292 of HSD11B1|
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Homo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 2|
|11-beta-HSD1; 11-DH; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1|
Entrez Gene 3290 Human
|The protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]|
|TransmembraneDruggable Genome C21-Steroid hormone metabolismAndrogen and estrogen metabolismMetabolic pathways|
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A: HepG2 (anti-HSD11B1 antibody diluted at 1:1000)
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HSD11B1(anti-HSD11B1 antibody) antibody at 1:200 dilution.