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OriGene Antibodies in recent publications
A common polymorphism in the LDL receptor gene has multiple effects on LDL receptor function Hum. Mol. Genet., Apr 2013; 22: 1424 - 1431. [anti-DDK]

Excitotoxicity Upregulates SARM1 Protein Expression and Promotes Wallerian-Like Degeneration of Retinal Ganglion Cells and Their Axons Invest. Ophthalmol. Vis. Sci., Apr 2013; 54: 2771 - 2780. [SARM1]

Modulation of TET2 expression and 5-methylcytosine oxidation by the CXXC domain protein IDAX Nature 497, 122-126 doi:10.1038/nature12052 [anti-DDK]

Natriuretic Peptide Receptor-3 Gene (NPR3): Nonsynonymous Polymorphism Results in Significant Reduction in Protein Expression Because of Accelerated Degradation Circ Cardiovasc Genet, Apr 2013; 6: 201 - 210. [NPR3]

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Home All anti-HSD11B1 antibodies

Anti-HSD11B1 Antibody

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA308504
  • Rabbit polyclonal antibody to HSD11B1 (hydroxysteroid (11-beta) dehydrogenase 1)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC405624) , 20ug
100ul $325 3-7 Days Add to Shopping Cart
WB(1)
IF(1)
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Also for HSD11B1 (NM_181755)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens hydroxysteroid (11-beta) dehydrogenase 1 (HSD11B1), transcript variant 2
Synonyms:11-beta-HSD1; 11-DH; CORTRD2; HDL; HSD11; HSD11B; HSD11L; SDR26C1
ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 232 and 292 of HSD11B1
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1mg/ml
Purification Purified by antigen-affinity chromatography. (Protein A or G Sepharose)
Guaranteed Application *WB, IF Suggested DilutionsWB:1:500-1:3000; IF:1:100-1:200;
BackgroundThe protein encoded by this gene is a microsomal enzyme that catalyzes the conversion of the stress hormone cortisol to the inactive metabolite cortisone. In addition, the encoded protein can catalyze the reverse reaction, the conversion of cortisone to cortisol. Too much cortisol can lead to central obesity, and a particular variation in this gene has been associated with obesity and insulin resistance in children. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq]
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
A: HepG2 (anti-HSD11B1 antibody diluted at 1:1000)
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed HeLa, using HSD11B1(anti-HSD11B1 antibody) antibody at 1:200 dilution.

 

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