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Home Antibody All anti-HRH3 antibodies

Anti-HRH3 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308494
  • Rabbit polyclonal antibody to Histamine H3 Receptor (histamine receptor H3)
100ul 325 3-7 Days
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WB(1)
IHC(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 293 and 387 of Histamine H3 Receptor (Uniprot ID#Q9Y5N1)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Rabbit, Rhesus Monkey, Guinea pig) Concentration9.74mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 49kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Affinity purified by Protein A.
Note Seq homology of immunogen across species: Mouse (87%), Rat (87%), Rabbit (85%), Rhesus Monkey (100%), Guinea pig (87%)

Reference Data

Target NameHomo sapiens histamine receptor H3 (HRH3)
Alternative NameGPCR97; HH3R
Database LinkNP_009163
Entrez Gene 11255 Human
Entrez Gene 99296 Mouse
Entrez Gene 85268 Rat
Entrez Gene 574253 Monkey
FunctionHistamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. This gene encodes one of the histamine receptors (H3) which belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and can regulate neurotransmitter release. This receptor can also increase voltage-dependent calcium current in smooth muscles and innervates the blood vessels and the heart in cardiovascular system. [provided by RefSeq]
Related PathwayTransmembraneDruggable Genome Neuroactive ligand-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431 . B: H1299. 10% SDS PAGE. TA308494 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded HeLa xenograft, using Histamine H3 Receptor(TA308494) antibody at 1:500 dilution.

 

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