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Home Antibody All anti-HMMR antibodies

Anti-HMMR Antibody Polyclonal


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA319659 Rabbit Polyclonal RHAMM Antibody 100ug $325 In Stock
LC415729 HMMR HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenRHAMM antibody was raised against a 18 amino acid synthetic peptide near the amino terminus of human RHAMM.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1 ug/mL, ICC: 2.5 ug/mL, IF: 5 ug/mL
BufferRHAMM Antibody is supplied in PBS containing 0.02% sodium azide.
Purification RHAMM Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens hyaluronan-mediated motility receptor (RHAMM) (HMMR), transcript variant 3
Alternative NameCD168; IHABP; RHAMM
Database LinkNP_036617
Entrez Gene 3161 Human
Entrez Gene 15366 Mouse
Entrez Gene 25460 Rat
FunctionRHAMM Antibody: The hyaluronan-mediated motility receptor, also known as RHAMM, was initially identified as a soluble protein that could be released by sub-confluent migrating cells, promoting cell motility and invasion via interactions with hyaluronan (HA) and the cell surface. While RHAMM is normally poorly expressed in most normal tissues and is not required for embryonic development or normal cell homeostasis functions, its expression is increased during wound repair in response to hypoxia and fibrogenic factors. However, its overexpression is transforming in multiple types of cancers and is required for maintaining RAS transformation. RHAMM associates with BRCA1 and BARD1, attenuating the mitotic-spindle-promoting activity of RHAMM, which may contribute to tumor progression by promoting genomic instability.
Related PathwayStem cell - PluripotencyDruggable Genome ECM-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of RHAMM in rat stomach tissue lysate with RHAMM antibody at 1 ug/mL.

IHC Image
Immunohistochemistry of RHAMM in human stomach tissue with RHAMM antibody at 2.5 ug/mL.

IF Image
Immunofluorescence of RHAMM in human stomach tissue with RHAM antibody at 20 ug/mL.


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