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Home Antibody All anti-HMGA1 antibodies

Anti-HMGA1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA305717
  • Goat Anti-HMGA1 (aa9-21) Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419517) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
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Also for HMGA1 (NM_002131)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-SQPLASKQEKDGT, from the internal region (near N Terminus) of the protein sequence according to NP_665906.1; NP_002122.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow, Pig Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 0.5-1ug/ml.
Buffer0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens high mobility group AT-hook 1 (HMGA1), transcript variant 2
Alternative NameHMG-R; HMGA1A; HMGIY
Database LinkNP_002122
Entrez Gene 3159 Human
Entrez Gene 15361 Mouse
Entrez Gene 117062 Rat
Entrez Gene 442946 Dog
FunctionThis gene encodes a non-histone protein involved in many cellular processes, including regulation of inducible gene transcription, integration of retroviruses into chromosomes, and the metastatic progression of cancer cells. The encoded protein preferentially binds to the minor groove of A+T-rich regions in double-stranded DNA. It has little secondary structure in solution but assumes distinct conformations when bound to substrates such as DNA or other proteins. The encoded protein is frequently acetylated and is found in the nucleus. At least seven transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayStem cell relevant signaling - JAK/STAT signaling pathwayStem cell - PluripotencyTranscription FactorsDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA305717 (0.5ug/ml) staining of Human Pancreas lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

 

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