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Home Antibody All anti-HLA-DQA1 antibodies

Anti-HLA-DQA1 Antibody EPR7300

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310579
  • Rabbit Monoclonal antibody against HLA-DQA1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400774) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(2)
Assay(1)
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Also for HLA-DQA1 (NM_002122)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human HLA-DQA1 was used as an immunogen.
Clone NameEPR7300 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsWB: 1:10000 - 1:50000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250
Predicted MW Explanation 28 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or ICC/IF.

Reference Data

Target NameHomo sapiens major histocompatibility complex, class II, DQ alpha 1 (HLA-DQA1)
Alternative NameCD; CELIAC1; DQ-A1; GSE; HLA-DQA
Database LinkNP_002113
Entrez Gene 100509457 Human
FunctionHLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides derived from extracellular proteins. Class II molecules are expressed in antigen presenting cells (APC: B Lymphocytes, dendritic cells, macrophages). The alpha chain is approximately 33-35 kDa. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifying the peptide binding specificities, resulting in up to four different molecules (1).
Related PathwayTransmembrane Cell adhesion molecules (CAMs)Antigen processing and presentationType I diabetes mellitusAsthmaAutoimmune thyroid diseaseSystemic lupus erythematosusMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HLA-DQA1 antibody [EPR7300]; All lanes : Anti-HLA-DQA1 antibody [EPR7300] at 1/10000 dilution.Lane 1 : Human lymph node lysate.Lane 2 : Daudi cell lysate .Lane 3 : Human spleen lysate .Lane 4 : Raji cell lysate .Lane 5 : Human tonsil lysate .Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 28 kDa.Observed band size : 33-35 kDa .
Assay Image
Other-Anti-HLA-DQA1 antibody [EPR7300](TA310579); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HLA-DQA1 antibody [EPR7300]; TA310579, at 1/100 dilution, staining HLA-DQA1 in paraffin-embedded Human colon tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-HLA-DQA1 antibody [EPR7300]; TA310579, at 1/100 dilution, staining HLA-DQA1 in paraffin-embedded Human tonsil tissue by Immunohistochemistry.

 

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