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Anti-HLA-C Antibody EPR6749
Also for HLA-C (NM_002117)
|A synthetic peptide corresponding to residues in human HLA-C was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC/IF or IHC-P.
|Homo sapiens major histocompatibility complex, class I, C (HLA-C), transcript variant 1|
|D6S204; HLA-JY3; HLC-C; PSORS1|
|HLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Mutations in HLA-C are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation (1).|
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Western blot - Anti-HLA-C antibody [EPR6749]; All lanes : Anti-HLA-C antibody [EPR6749] at 1/1000 dilution.Lane 1 : Jurkat lysate.Lane 2 : Human melanoma lysate.Lane 3 : Human placenta lysate.Lane 4 : 293T lysate.Lane 5 : A375 lysate.Predicted band size : 41 kDa.