OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-HLA-C antibodies

Anti-HLA-C Antibody EPR6749

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310578
  • Rabbit Monoclonal antibody against HLA-C
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419521) , 20ug Explanation
100ul 325 3-7 Days
Add to Shopping Cart
WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human HLA-C was used as an immunogen.
Clone NameEPR6749 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100
Predicted MW Explanation 41 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF or IHC-P.

Reference Data

Target NameHomo sapiens major histocompatibility complex, class I, C (HLA-C), transcript variant 1
Alternative NameD6S204; HLA-JY3; HLC-C; PSORS1
Database LinkNP_002108
Entrez Gene 3107 Human
FunctionHLA-C belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). The heavy chain is anchored in the membrane. Class I molecules play a central role in the immune system by presenting peptides derived from endoplasmic reticulum lumen. They are expressed in nearly all cells. The heavy chain is approximately 45 kDa. Mutations in HLA-C are responsible for the peptide binding specificity of each class one molecule. Typing for these polymorphisms is routinely done for bone marrow and kidney transplantation (1).
Related PathwaySecreted ProteinTransmembrane EndocytosisCell adhesion molecules (CAMs)Antigen processing and presentationNatural killer cell mediated cytotoxicityType I diabetes mellitusAutoimmune thyroid diseaseMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-HLA-C antibody [EPR6749]; All lanes : Anti-HLA-C antibody [EPR6749] at 1/1000 dilution.Lane 1 : Jurkat lysate.Lane 2 : Human melanoma lysate.Lane 3 : Human placenta lysate.Lane 4 : 293T lysate.Lane 5 : A375 lysate.Predicted band size : 41 kDa.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title