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Home Antibody All anti-HIF1AN antibodies

Anti-HIF1AN Antibody FIH 162c

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA326397
  • Mouse monoclonal FIH Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402628) , 20ug
100µg $325 3-7 Days
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WB(1)
IHC(1)
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Also for HIF1AN (NM_017902)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFull length human FIH expressed in E.coli BL21 (DE3) cells
Clone NameFIH 162c IsotypeIgG1
Species ReactivityHuman Concentration1mg/mL
Guaranteed Application *WB, IHC Suggested DilutionsWB: 10ug/ml
BufferPBS pH7.4, 50% glycerol, 0.09% sodium azide
Purification Protein G Purified
Note Detects ~45kDa (human) proteins, corresponding to the molecular mass of FIH on SDS PAGE immunoblots

Reference Data

Target NameHomo sapiens hypoxia inducible factor 1, alpha subunit inhibitor (HIF1AN)
Alternative NameFIH1
Database LinkNP_060372
FunctionFIH, Factor inhibiting HIF1 (hypoxia-inducible factor), is an asparaginyl hydroxylase. FIH in conjunction with VHL represses HIF-1 transcriptional activity by disrupting the interaction of HIF-1 with the transcriptional coactivators CBP/p300, and by recruiting histone deacetylases. FIH activity is inhibited during hypoxia . Recent studies show that low nuclear expression of FIH is a strong independent prognostic factor for a poor overall survival in clear cell renal cell cancinoma .
Related Pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of FIH in a human cell line mix, using a 1:1000 dilution of the antibody
IHC Image
FIH visualized using the antibody

 

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