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Home Antibody All anti-HIF1AN antibodies

Anti-HIF1AN Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA301533
  • Rabbit Polyclonal Antibody against Factor Inhibiting HIF-1
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC402628) , 20ug
100ul 325 In Stock
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WB(1)
IHC(1)
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Also for HIF1AN (NM_017902)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA C-terminal region synthetic peptide made to the human FIH protein sequence (between residues 300 and the C-terminus).
Clone Name IsotypeIgG
Species Reactivityhuman, rat Concentration1.25 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 1000-1:5000
BufferTris-citrate/phosphate [pH 7-8] buffer. and 0.1% Sodium Azide
Purification Immunogen affinity purified

Reference Data

Target NameHomo sapiens hypoxia inducible factor 1, alpha subunit inhibitor (HIF1AN)
Alternative NameFIH1
Database LinkNP_060372
FunctionFactor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.
Related Pathway

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WB Image
Detection of FIH-1 in rat and human samples
IHC Image
Detection of FIH-1 in rat brain tissue (1:100).

 

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