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Home Antibody All anti-HES1 antibodies

Anti-HES1 CONJUGATED Antibody Clone OTI4H1

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SKU Description Amount Price Availability*  
TA400013 Anti-HES1 mouse mAb, clone OTI4H1, HRP conjugated 100 ul $325 In Stock
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WB(1)

OriGene Data

ImmunogenRecombinant protein expressed in E.coli corresponding to amino acids 1-280 of human HES1
Clone NameClone OTI4H1 IsotypeIgG1
Species ReactivityHuman Concentration0.52 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
Predicted MW Explanation 29.4 kDa
BufferPBS (pH7.4) containing 50% glycerol, 0.1% BSA and 0.02% NaN3

Reference Data

Target NameHomo sapiens hes family bHLH transcription factor 1 (HES1)
Alternative NamebHLHb39; HES-1; HHL; HRY
Database LinkNP_005515
FunctionThis protein belongs to the basic helix-loop-helix family of transcription factors. It is a transcriptional repressor of genes that require a bHLH protein for their transcription. The protein has a particular type of basic domain that contains a helix interrupting protein that binds to the N-box rather than the canonical E-box.
Related PathwayStem cell relevant signaling - DSL/Notch pathwayES Cell Differentiation/IPSAdult stem cellsCancer stem cellsTranscription FactorsDruggable Genome Notch signaling pathwayMaturity onset diabetes of the young

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* OriGene provides validated application data and protocol, with money back guarantee.

HEK293T cells were transfected with pCMV6-ENTRY control (Lane 1) or pCMV6-ENTRY HES1 (Lane 2) plasmids for 48 hrs. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-HES1-HRP.
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