OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-HDAC1 antibodies

Anti-HDAC1 Antibody

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA322693
  • Anti-HDAC1 Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417624) , 20ug Explanation
100ul 325 2-3 Weeks
Add to Shopping Cart
spacer
WB(1)
IHC(1)
spacer
Also for HDAC1 (NM_004964)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 469-482 amino acids of Human histone deacetylase 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:25-100
Predicted MW Explanation 55kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens histone deacetylase 1 (HDAC1)
Alternative NameGON-10; HD1; RPD3; RPD3L1
Database LinkNP_004955
Entrez Gene 3065 Human
Entrez Gene 433759 Mouse
Entrez Gene 297893 Rat
FunctionHistone acetylation and deacetylation; catalyzed by multisubunit complexes; play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2; it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell - PluripotencyAdult stem cellsTranscription FactorsDruggable Genome Cell cycleNotch signaling pathwayHuntington's diseasePathways in cancerChronic myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Predicted band size: 55 kDa . Positive control: Human colon and kidney cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Human colon tissue lysate Lane2: Human kidney cancer tissue lysate Lysates: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes)
IHC Image
Predicted cell location: Cytoplasm, Nucleus. Positive control: Human ovarian cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using HDAC1 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200)

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title