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Home Antibody All anti-HDAC1 antibodies

Anti-HDAC1 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA322693 Anti-HDAC1 Rabbit Polyclonal Antibody 100ul $325 2-3 Weeks
LC417624 HDAC1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)
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Also for HDAC1 (NM_004964)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenSynthetic peptide corresponding to a region derived from 469-482 amino acids of Human histone deacetylase 1
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.8mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:1000-5000, WB: 1:200-1000, IHC: 1:25-100
Predicted MW Explanation 55kDa
BufferPBS pH7.3, 0.05% NaN3, 50% glycerol
Purification Antigen affinity purification

Reference Data

Target NameHomo sapiens histone deacetylase 1 (HDAC1)
Alternative NameGON-10; HD1; RPD3; RPD3L1
Database LinkNP_004955
Entrez Gene 3065 Human
Entrez Gene 433759 Mouse
Entrez Gene 297893 Rat
FunctionHistone acetylation and deacetylation; catalyzed by multisubunit complexes; play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2; it deacetylates p53 and modulates its effect on cell growth and apoptosis.
Related PathwayStem cell relevant signaling - DSL/Notch pathwayStem cell - PluripotencyAdult stem cellsTranscription FactorsDruggable Genome Cell cycleNotch signaling pathwayHuntington's diseasePathways in cancerChronic myeloid leukemia

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Predicted band size: 55 kDa . Positive control: Human colon and kidney cancer tissue lysate. Recommended dilution: 1/200-1000. (Gel: 10%SDS-PAGE Lane1: Human colon tissue lysate Lane2: Human kidney cancer tissue lysate Lysates: 40 ug per lane Primary antibody: 1/400 dilution Secondary antibody: Goat anti Rabbit IgG - H&L (HRP) at 1/10000 dilution Exposure time: 2 minutes)
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Predicted cell location: Cytoplasm, Nucleus. Positive control: Human ovarian cancer tissue. Recommended dilution: 1/25-100 The image on the left is immunohistochemistry of paraffin-embedded Human ovarian cancer tissue using HDAC1 antibody at dilution 1/20, on the right is treated with the synthetic peptide. (Original magnification:x200)
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