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Anti-HCK Antibody EP2415Y
|A synthetic peptide corresponding to residues near the C-terminus of human Hck was used as an immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:20,000; ICC: 1:100; FC: 1:60
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens HCK proto-oncogene, Src family tyrosine kinase (HCK), transcript variant 1|
Entrez Gene 3055 Human
|The protein encoded by this gene is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization. [provided by RefSeq]. |
|Protein KinaseDruggable Genome Chemokine signaling pathwayFc gamma R-mediated phagocytosis|
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Western blot - Hck antibody [EP2415Y]; Anti-Hck antibody [EP2415Y] at 1/200000 dilution + TF-1 cell lysate at 10 ug.Secondary.goat anti-rabbit HRP at 1/2000 dilution.Predicted band size : 59 kDa.Observed band size : 59 kDa.