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Home Antibody All anti-HAVCR2 antibodies

Anti-HAVCR2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302624
  • Goat Polyclonal Antibody against TIM3 / HAVCR2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403200) , 20ug
100ug 325 3-7 Days
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WB(1)
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Also for HAVCR2 (NM_032782)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenPeptide with sequence C-KWYSHSKEKIQN, from the internal region of the protein sequence according to NP_116171.3.
Clone Name IsotypeGoat IgG
Species ReactivityHuman, Dog Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:32,000. WB: 0.3-1.0µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens hepatitis A virus cellular receptor 2 (HAVCR2)
Alternative NameHAVcr-2; KIM-3; Tim-3; TIM3; TIMD-3; TIMD3
Database LinkNP_116171
FunctionCD4 (MIM 186940)-positive T helper lymphocytes can be divided into types 1 (Th1) and 2 (Th2) on the basis of their cytokine secretion patterns. Th1 cells and their associated cytokines are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions, whereas Th2 cells are involved in the control of extracellular helminthic infections and the promotion of atopic and allergic diseases. The 2 types of cells also cross-regulate the functions of the other. TIM3 is a Th1-specific cell surface protein that regulates macrophage activation and enhances the severity of experimental autoimmune encephalomyelitis in mice.[supplied by OMIM].
Related Pathway

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WB Image
TA302624 (0.3µg/ml) staining of human tonsil lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.

 

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