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Home Antibody All anti-HADHB antibodies

Anti-HADHB Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308352
  • Rabbit polyclonal antibody to HADHB (hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), beta subunit)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424879) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenSynthetic peptide corresponding to a region within amino acids 1 and 43 of HADHB (Uniprot ID#P55084)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Chimpanzee) Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 51kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Chimpanzee (100%)

Reference Data

Target NameHomo sapiens hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit (HADHB), transcript variant 1
Alternative NameECHB; MSTP029; MTPB; TP-BETA
Database LinkNP_000174
Entrez Gene 3032 Human
FunctionThis gene encodes the beta subunit of the mitochondrial trifunctional protein, which catalyzes the last three steps of mitochondrial beta-oxidation of long chain fatty acids. The mitochondrial membrane-bound heterocomplex is composed of four alpha and four beta subunits, with the beta subunit catalyzing the 3-ketoacyl-CoA thiolase activity. Mutations in this gene result in trifunctional protein deficiency. The encoded protein can also bind RNA and decreases the stability of some mRNAs. The genes of the alpha and beta subunits of the mitochondrial trifunctional protein are located adjacent to each other in the human genome in a head-to-head orientation. Alternatively spliced transcript variants have been found; however, their full-length nature is not known. [provided by RefSeq]
Related Pathway Fatty acid elongation in mitochondriaFatty acid metabolismValine, leucine and isoleucine degradationMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (30 ug of whole cell lysate). A: A431 . 10% SDS PAGE. HADHB antibody. TA308352 diluted at 1:1000.

 

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