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Anti-GZMB Antibody EPR8260

IHC(1)

Gene Name Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) Synonyms: CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT Immunogen A synthetic peptide corresponding to residues in human Granzyme B was used as an immunogen. Buffer Store at -20 °C. Buffer: Antibody buffer, sodium azide, glycerol, and BSA. Stable for 12 months from date of receipt. Clone Name EPR8260 Isotype Species Reactivity Human, Mouse, Rat Concentration Purification (Protein A or G Sepharose) Guaranteed Application * IHC Suggested Dilutions WB: 1:1,000 - 10,000; Background Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response (1). Related Pathway Apoptosis

Related Lysate from OriGene • Transient overexpression lysate of granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) Anti-Tag Antibodies & WB Reagent • Anti-Tag Antibodies • Western Blot Reagent shRNA • GZMB - Human, 4 unique 29mer shRNA constructs in retroviral RFP vector • GZMB - Human, 4 unique 29mer shRNA constructs in retroviral GFP vector • Gzmb - Mouse, 4 unique 29mer shRNA constructs in retroviral GFP vector • GZMB - Human, 4 unique 29mer shRNA constructs in retroviral untagged vector • Gzmb - Mouse, 4 unique 29mer shRNA constructs in retroviral untagged vector Related ORF Clones • Myc-DDK-tagged ORF clone of Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) as transfection-ready DNA • GFP-tagged ORF clone of Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) as transfection-ready DNA • Myc-DDK-tagged ORF clone of Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) as 200 ug transfection-ready DNA Related cDNA Clones • Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB) as transfection-ready DNA

Conjugation Services
OriGene provides conjugation services of TrueMAB antibodies with the following molecules:

• HRP
• Biotin
• PE
• FITC
• DyLight® 488
• DyLight® 550
• DyLight® 594
• DyLight® 633

* DyLight is a trademark of Thermo-Fisher Scientific

Bulk Order
OriGene offers bulk sizes of TrueMAB antibodies in both the BSA/glycerol formulation and the carrier-free (BSA/glycerol-free) formulation.

Contact us with your conjugation/bulk request: antibody@origene.com or 888-267-4436 (Tech Support)