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Anti-GZMB Antibody EPR8260
Also for GZMB (NM_004131)
|A synthetic peptide corresponding to residues in human Granzyme B was used as an immunogen.|
||Tissue culture supernatant
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250; IP: 1:10 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for WB.|
|Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for WB.
|Homo sapiens granzyme B (granzyme 2, cytotoxic T-lymphocyte-associated serine esterase 1) (GZMB)|
|CCPI; CGL-1; CGL1; CSP-B; CSPB; CTLA1; CTSGL1; HLP; SECT|
|Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens, usually peptides or proteins resulting from infection by intracellular pathogens. Granzyme B is crucial for the rapid induction of target cell apoptosis by CTL in cell-mediated immune response (1). |
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Other-Anti-Granzyme B antibody [EPR8260](ab134933); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Granzyme B antibody [EPR8260]; Immunohistochemical analysis of paraffin-embedded, formalin-fixed Human Hodgkin's lymphoma tissue, labelling Granzyme B using ab134933 at a 1/100 dilution.