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Anti-GSTM1 Antibody EPR1936(2)
Also for GSTM1 (NM_146421)
|A synthetic peptide corresponding to residues in human GSTM1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens glutathione S-transferase mu 1 (GSTM1), transcript variant 2|
|GST1; GSTM1-1; GSTM1a-1a; GSTM1b-1b; GTH4; GTM1; H-B; MU; MU-1|
Entrez Gene 2944 Human
Entrez Gene 14862 Mouse
Entrez Gene 24423 Rat
|GSTM1 is a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The proteins that belong to the mu class of enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Null mutations of this class mu protein have been linked with an increase in a number of cancers, likely due to an increased susceptibility to environmental toxins and carcinogens (1).|
|Druggable Genome Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450|
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Western blot - Glutathione S Transferase mu antibody [EPR1936(2)]; All lanes : Anti-Glutathione S Transferase mu antibody [EPR1936(2)] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HepG2 cell lysate.Lane 3 : SH-SY5Y cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 26 kDa.