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Home Antibody All anti-GSTK1 antibodies

Anti-GSTK1 Antibody EPR1939

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307095
  • Rabbit monoclonal antibody against Gstk1 (clone EPR1939 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC414320) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
IHC(1)
IF(1)
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Also for GSTK1 (NM_015917)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Gstk1was used as an immunogen.
Clone NameEPR1939 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsIHC-P: 1:250 - 1:500; WB: 1:1000 - 1:10000; IP: 1:30; FC: 1:60; ICC/IF: 1:250 - 1:500
Predicted MW Explanation 25 kDa
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens glutathione S-transferase kappa 1 (GSTK1), transcript variant 1
Alternative NameGST; GST 13-13; GST13; GST13-13; GSTK1-1; hGSTK1
Database LinkNP_057001
Entrez Gene 373156 Human
FunctionGlutathione transferases (Gst) are a superfamily of enzymes that play a vital functional role in the cellular detoxification process. They catalyze the conjugation of the thiol group of glutathione to the electrophilic groups of a wide range of hydrophobic substrates, leading to an easier removal of the latter from the cells. The kappa class (Gstk) is the least studied one among various classes within the superfamily. The TRX-like domain of Gstk shares 19% sequence identity and structure similarity with the theta class Gst, suggesting that the kappa class is more closely related to the theta class enzyme within the Gst superfamily (1). Research has demonstrated that Gstk1 is expressed at relatively high levels in liver and stomach, and at moderate levels in kidney, heart, large intestine, testis, and lung. Sparse or essentially no Gstk1 protein was reported to be detected in small intestine, brain, spleen, and skeletal muscle (2).
Related Pathway Glutathione metabolismMetabolism of xenobiotics by cytochrome P450Drug metabolism - cytochrome P450

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Glutathione S Transferase kappa 1 antibody [EPR1939]; All lanes : Anti-Glutathione S Transferase kappa 1 antibody [EPR1939] at 1/1000 dilution.Lane 1 : Human fetal liver lysate.Lane 2 : Human heart lysate.Lane 3 : 293T cell lysate.Lane 4 : HeLa cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 25 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Glutathione S Transferase kappa 1 antibody [EPR1939]; Immunohistochemical analysis of paraffin-embedded Human liver tissue labelling Glutathione S Transferase kappa 1 with TA307095 at 1/250 dilution.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Glutathione S Transferase kappa 1 antibody [EPR1939]; Immunofluorescent analysis of HeLa cells labelling Glutathione S Transferase kappa 1 with TA307095 at 1/250 dilution.

 

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