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Home Antibody All anti-GRIK2 antibodies

Anti-GRIK2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306496
  • Rabbit Polyclonal Grik2 Antibody
100ug 325 3-7 Days
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WB(1)

OriGene Data

ImmunogenGrik2 antibody was raised against a 13 amino acid peptide near the carboxy terminus of the human Grik2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB Suggested DilutionsWB: 0.5 - 1 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens glutamate receptor, ionotropic, kainate 2 (GRIK2), transcript variant 3
Alternative NameEAA4; GLR6; GluK2; GLUK6; GLUR6; MRT6
Database LinkNP_001159719
Entrez Gene 2898 Human
Entrez Gene 14806 Mouse
Entrez Gene 54257 Rat
FunctionGlutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik2, also known as glutamate receptor 6, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Recent reports have suggested that defects in the Grik2 protein may be associated with autosomal recessive mental retardation and possibly other neurological disorders such as schizophrenia. Numerous isoforms of Grik2 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow. This Grik2 antibody may exhibit some cross-reactivity to Grik3.
Related PathwayTransmembraneIon Channels: Glutamate ReceptorsDruggable Genome Neuroactive ligand-receptor interaction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of Grik2 in human brain tissue lysate with Grik2 antibody at (A) 0.5 and (B) 1 µg/ml.

 

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