Home Antibody All anti-GRIA4 antibodies
Also for GRIA4 (NM_000829)
|Peptide with sequence C-KKLDQREYPGSETP, from the internal region of the protein sequence according to NP_000820.3; NP_001070711.1; NP_001070712.1.|
|Test: Human. Expected from seq similarity: Human, Mouse, Rat, Cow
||Lot dependent; please refer to CoA along with shipment
|0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20C. Minimize freezing and thawing.
|Homo sapiens glutamate receptor, ionotropic, AMPA 4 (GRIA4), transcript variant 1|
|GluA4; GLUR4; GLUR4C; GLURD|
Entrez Gene 2893 Human
Entrez Gene 14802 Mouse
Entrez Gene 29629 Rat
|Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The subunit encoded by this gene belongs to a family of AMPA (alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate)-sensitive glutamate receptors, and is subject to RNA editing (AGA->GGA; R->G). Alternative splicing of this gene results in transcript variants encoding different isoforms, which may vary in their signal transduction properties. Some haplotypes of this gene show a positive association with schizophrenia. [provided by RefSeq]. |
|TransmembraneIon Channels: Glutamate ReceptorsDruggable Genome Neuroactive ligand-receptor interaction|
* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.
TA305853 (0.3ug/ml) staining of Human Cerebellum lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.