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Home Antibody All anti-GRB2 antibodies

Anti-GRB2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302665
  • Goat Polyclonal Antibody against GRB2
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400765) , 20ug Explanation
100ug 325 3-7 Days
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WB(1)
IHC(1)
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Also for GRB2 (NM_002086)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-PRNYVTPVNRNV, from the C Terminus of the protein sequence according to NP_002077.1; NP_987102.1.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human, Mouse. Expected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsELISA: 1:32,000. WB: 0.05-0.15ug/ml. IHC: 0.1-0.3ug/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens growth factor receptor-bound protein 2 (GRB2), transcript variant 1
Alternative NameASH; EGFRBP-GRB2; Grb3-3; MST084; MSTP084; NCKAP2
Database LinkNP_002077
Entrez Gene 2885 Human
Entrez Gene 14784 Mouse
Entrez Gene 81504 Rat
Entrez Gene 483312 Dog
FunctionThe protein encoded by this gene binds the epidermal growth factor receptor and contains one SH2 domain and two SH3 domains. Its two SH3 domains direct complex formation with proline-rich regions of other proteins, and its SH2 domain binds tyrosine phosphorylated sequences. This gene is similar to the Sem5 gene of C.elegans, which is involved in the signal transduction pathway. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayDruggable Genome MAPK signaling pathwayErbB signaling pathwayChemokine signaling pathwayDorso-ventral axis formationFocal adhesionGap junctionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302665 staining (2µg/ml) of Jurkat lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.
IHC Image
TA302665 (0.3ug/ml) staining of paraffin embedded Human Tonsil. Microwaved antigen retrieval with citrate buffer pH6, HRP-staining.

 

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