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Home Antibody All anti-GRB10 antibodies

Anti-GRB10 Antibody Polyclonal

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA319657
  • Rabbit Polyclonal GRB10 Antibody
100ug 325 3-7 Days
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WB(1)
IF(1)

OriGene Data

ImmunogenGRB10 antibody was raised against a 17 amino acid synthetic peptide near the carboxy terminus of human GRB10.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsELISA, WB: 1 - 2 ug/ml, IF: 20 ug/ml
BufferGRB10 Antibody is supplied in PBS containing 0.02% sodium azide.
Purification GRB10 Antibody is affinity chromatography purified via peptide column.

Reference Data

Target NameHomo sapiens growth factor receptor-bound protein 10 (GRB10), transcript variant 1
Alternative NameGrb-10; GRB-IR; IRBP; MEG1; RSS
Database LinkNP_005302
FunctionGRB10 Antibody: GRB10 belongs to a small family of adapter proteins that are known to interact with a number of receptor tyrosine kinases and signaling molecules and function in diverse cellular processes. GRB10 is a growth factor receptor-binding protein that interacts with insulin receptors and insulin-like growth-factor receptors. Overexpression of some isoforms of GRB10 inhibits tyrosine kinase activity and results in growth suppression. GRB10 can also interact with the L isoform of the proapoptotic protein Bim. This gene is imprinted in a highly isoform- and tissue-specific manner, with expression observed from the paternal allele in the brain, and from the maternal allele in the placental trophoblasts.
Related Pathway
EGFR1 Signaling Pathway

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WB Image
Western blot analysis of GRB10 in SK-N-SH cell lysate with GRB10 antibody at (A) 1 and (B) 2 ug/mL.
IF Image
Immunofluorescence of GRB10 in rat brain cells with GRB10 antibody at 20 ug/mL.

 

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