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Home Antibody All anti-GNB2L1 antibodies

Anti-GNB2L1 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA302104
  • Rabbit Polyclonal Antibody against GNB2L1 (N-term)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC401838) , 20ug
100ug $325 In Stock
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WB(1)
IHC(1)
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Also for GNB2L1 (NM_006098)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human GNB2L1.
Clone Name IsotypeRabbit Ig
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1: 100~500; IHC: 1:50~100; ELISA: 1: 1,000;
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.

Reference Data

Target NameHomo sapiens guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 (GNB2L1)
Alternative NameGnb2-rs1; H12.3; HLC-7; PIG21; RACK1
Database LinkNP_006089
FunctionProtein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The STE group (homologs of yeast Sterile 7, 11, 20 kinases) consists of 50 kinases related to the mitogen-activated protein kinase (MAPK) cascade families (Ste7/MAP2K, Ste11/MAP3K, and Ste20/MAP4K). MAP kinase cascades, consisting of a MAPK and one or more upstream regulatory kinases (MAPKKs) have been best characterized in the yeast pheromone response pathway. Pheromones bind to Ste cell surface receptors and activate yeast MAPK pathway.
Related Pathway

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WB Image
(LEFT)The anti-GNB2L1 Pab is used in Western blot to detect GNB2L1 in Ramos cell lysate. (RIGHT)Western blot analysis of GNB2L1 (arrow) using GNB2L1 Antibody (N-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the GNB2L1 gene (Lane 2) (Origene Technologies).
IHC Image
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

 

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