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Home Antibody All anti-GHR antibodies
UltraMAB

Anti-GHR GAT Antibody Polyclonal

Generated by Genomic Immunization

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SKU Description Amount Price Availability*  
TA590807 Rabbit Polyclonal Growth hormone receptor Antibody 50ug $325 In Stock
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ELISA(1)

OriGene Data

ImmunogenDNA immunization. This antibody is specific for the Middle Region of the target protein.
Clone NamePolyclonal IsotypeIgG
Species ReactivityHuman Concentration0.96mg/ml
Guaranteed Application *ELISA Suggested DilutionsWB: 1:5000-1:20000; ELISA: 1:100-1:2000
Buffer20 mM Potassium Phosphate, 150 mM Sodium Chloride, pH 7.0
Purification The fragment used for DNA immunization was expressed in E.coli and the purified protein fragment was used for affinity purification of the antibody.
Note This antibody was generated by SDIX's Genomic Antibody Technology ® (GAT). Learn about GAT

Reference Data

Target NameHomo sapiens growth hormone receptor (GHR), transcript variant 1
Alternative NameGHBP; GHIP
Database LinkNP_000154
Entrez Gene 2690 Human
FunctionThis gene encodes a protein that is a transmembrane receptor for growth hormone. Binding of growth hormone to the receptor leads to receptor dimerization and the activation of an intra- and intercellular signal transduction pathway leading to growth. A common alternate allele of this gene, called GHRd3, lacks exon three and has been well-characterized. Mutations in this gene have been associated with Laron syndrome, also known as the growth hormone insensitivity syndrome (GHIS), a disorder characterized by short stature. Other splice variants, including one encoding a soluble form of the protein (GHRtr), have been observed but have not been thoroughly characterized.
Related PathwayTransmembraneDruggable Genome Cytokine-cytokine receptor interactionNeuroactive ligand-receptor interactionJak-STAT signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

ELISA: Growth hormone receptor Antibody
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