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Home Antibody All anti-GFAP antibodies

Anti-GFAP Antibody EPR1034Y


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA301159 Rabbit Monoclonal Antibody against GFAP (Clone EPR1034Y) 100ul $325 In Stock
LC419563 GFAP HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in the N-term of human GFAP was used as immunogen.
Clone NameEPR1034Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:50000 - 1:100000; IP: 1:40; IHC-P: 1:250 - 1:500; ICC/IF: 1:100 - 1:250
Predicted MW Explanation 50 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens glial fibrillary acidic protein (GFAP), transcript variant 1
Alternative NameALXDRD
Database LinkNP_002046
Entrez Gene 2670 Human
Entrez Gene 14580 Mouse
Entrez Gene 24387 Rat
FunctionGlial fibrillary acidic protein (GFAP) belongs to the class III of the intermediate filament (IF) proteins highly specific to astrocytes which function as nerve cells in the brain and in the central nervous system (CNS) (1-2). Two other class III IF proteins, nestin and vimentin, dominate in immature astrocytes, while GFAP is most abundant in mature astrocytes (3). GFAP is used as a marker to distinguish astrocytes form other glial cells during development. Mutations in GFAP cause Alexander disease, a rare disorder of the CNS. Most frequent mutations are located at Arginine 79 or 239 (4).
Related PathwayES Cell Differentiation/IPS

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - GFAP antibody [EPR1034Y]; All lanes : Anti-GFAP antibody [EPR1034Y] at 1/5000 dilution.Lane 1 : Human brain lysate.Lane 2 : Rat brain lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-Rabbit antibody at 1/2000 dilution.Predicted band size : 50 kDa.Observed band size : 50 kDa.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-GFAP antibody [EPR1034Y]; Immunohistochemistry on formalin-fixed paraffin-embedded mouse brain using TA301159.

IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - GFAP antibody [EPR1034Y]; Immunohistochemical analysis of paraffin-embedded human brain (left) and human glioma (right) using TA301159


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