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 Home All anti-GCK antibodies

Anti-GCK TrueMAB Antibody clone 3E3

TrueMAB™ Antibodies - Made against Authentic Protein Antigens

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Specifications Related Products Conjugation/Bulk FAQs
SKU Description Amount Price Availability*  
TA500459
  • Purified GCK mouse monoclonal antibody, clone 3E3
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400059) , 20ug
 100ul $379 In Stock Add to Shopping Cart
CF500459
  • Carrier-free (BSA/glycerol-free) GCK mouse monoclonal antibody, clone 3E3
100ug $450 8-10 Days Add to Shopping Cart
WB(1)
IHC(9)
IF(1)
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Also for GCK (NM_000162)
cDNA Clone shRNA/siRNA Lysate Protein Antibody
Gene NameHomo sapiens glucokinase (hexokinase 4) (GCK), transcript variant 1
Synonyms:FGQTL3; GK; GLK; HHF3; HK4; HKIV; HXKP; LGLK; MODY2
ImmunogenFull length human recombinant protein of human GCK (NP_000153) produced in HEK293T cell.
BufferPBS (pH 7.3) containing 1% BSA, 50% glycerol and 0.02% sodium azide.
Clone Nameclone 3E3 IsotypeIgG1
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Purification Purified from mouse ascites fluids by affinity chromatography (Protein A or G Sepharose)
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB 1:500, IHC 1:50, IF 1:50,
BackgroundHexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI). [provided by RefSeq].
Related Pathway
MAPK signaling pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY GCK (RC200472, Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-GCK.
IHC Image
Immunohistochemical staining of paraffin-embedded Human breast tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Human Kidney tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human kidney tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Human lung tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human lung tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Human pancreas tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human thyroid tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IHC Image
Immunohistochemical staining of paraffin-embedded Carcinoma of Human prostate tissue using anti-GCK mouse monoclonal antibody. (TA500459)
IF Image
Anti-GCK mouse monoclonal antibody (TA500459) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY GCK(RC200472).

 

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