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Home Antibody All anti-GAD2 antibodies

Anti-GAD2 Antibody EPR2553Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA303520
  • Rabbit monoclonal antibody against GAD2 (EPR2553Y )
  • FREE positive control: HEK293T cell transient overexpression lysate (LC424506) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for GAD2 (NM_000818)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human GAD2 was used as an immunogen.
Clone NameEPR2553Y IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:500 - 1:2000
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens glutamate decarboxylase 2 (pancreatic islets and brain, 65kDa) (GAD2), transcript variant 1
Alternative NameGAD65
Database LinkNP_000809
FunctionThis gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantibody and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Alternative splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq].
Related Pathway

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WB Image
Western blot - GAD65 antibody [EPR2553Y]; All lanes : Anti-GAD65 antibody [EPR2553Y] at 1/1000 dilution.Lane 1 : Fetal brain lysate.Lane 2 : Mouse brain lysate.Lane 3 : Rat brain lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 65 kDa.Observed band size : 70 kDa .Additional bands at : 80 kDa. We are unsure as to the identity of these extra bands.

 

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