Homo sapiens gamma-aminobutyric acid (GABA) B receptor, 2 (GABBR2)
Synonyms:
GABABR2; GPR51; GPRC3B; HG20; HRIHFB2099
Immunogen
A phospho-specific peptide corresponding residues surrounding serine 884 of human GABAB R2 was used as an immunogen. This antibody detects GABAB R2 phosphorylated at serine 884.
Buffer
50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
B-type receptors for the neurotransmitter GABA (gamma-aminobutyric acid) inhibit neuronal activity through G protein-coupled second-messenger systems, which regulate the release of neurotransmitters and the activity of ion channels and adenylyl cyclase. See GABBR1 (MIM 603540) for additional background information on GABA-B receptors.[supplied by OMIM].
Related Pathway
Signaling by GPCR
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Western blot analysis on human brain lysates using anti-Phospho-GABAB R2 (pS884) RabMAb (TA303869), 1:5000 dilution. Cells were either (A) untreated (B) treated with AP.
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