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Home Antibody All anti-FTO antibodies

Anti-FTO Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA306766
  • Rabbit Polyclonal FTO Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC421649) , 20ug
100ug $325 3-7 Days
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WB(1)
IHC(1)
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Also for FTO (NM_001080432)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenFTO antibody was raised against a 15 amino acid peptide from near the amino terminus of human FTO.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1 - 2 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens fat mass and obesity associated (FTO)
Alternative NameALKBH9
Database LinkNP_001073901
FunctionRising obesity rates are rapidly becoming a growing health concern in the developing world. The fat mass and obesity associated gene (FTO) is the first gene discovered to contribute to common forms of human obesity. FTO is a member of the non-heme dioxygenase superfamily, encoding a 2-oxoglutarate-dependent nucleic acid demethylase whose mRNA is widely expressed, especially in neurons of feeding-related nuclei of the brain. FTO mRNA in the arcuate nucleus in mice is up-regulated by feeding and down-regulated during fasting, although the opposite pattern has been observed in rats. At least four isoforms of FTO are known to exist.
Related Pathway

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WB Image
Western blot analysis of FTO in human uterus tissue lysate with FTO antibody at (A) 1 and (B) 2 ug/ml.
IHC Image
Immunohistochemistry of FTO in mouse brain tissue with FTO antibody at 2.5 ug/ml.

 

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