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Anti-FTL Antibody EPR5260
|A synthetic peptide corresponding to residues on the C-terminus in human Ferritin was used as an immunogen. This antibody recognizes the light chain only.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; FC: 1:100 - 1:500
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for ICC or IHC-P.
|Homo sapiens ferritin, light polypeptide (FTL)|
|Ferritin is important in iron homeostasis. It is the main iron-storage protein, composed of two partially homologous subunits, heavy and light chains. Ferritin molecules in cells containing high levels of iron tend to be rich in light chains and may have a long-term storage function, whereas heavy-rich ferritins are more active in iron metabolism (1, 2). Mutations in ferritin cause hereditary hyperferritinemia-cataract syndrome and neuroferritinopathy, associated with inflammation. Elevated levels of ferritin are reported as characteristics of adult-onset Still's disease and hemophagocytic syndrome, also associated with inflammation (3).|
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Western blot - Ferritin Light Chain antibody [EPR5260]; All lanes : Anti-Ferritin Light Chain antibody [EPR5260] at 1/10000 dilution.Lane 1 : Fetal liver lysate.Lane 2 : HepG2 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 20 kDa.Observed band size : 19 kDa .
Flow Cytometry - Ferritin Light Chain antibody [EPR5260]; Flow cytometric analysis of permeabilized HeLa cells using TA307874 at a dilution of 1/100 (red) or a rabbit IgG (negative) (green).