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Home Antibody All anti-FKTN antibodies

Anti-FKTN Antibody EPR7913

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310490
  • Rabbit Monoclonal antibody against Fukutin (FKTN)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC421539) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
Assay(1)
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Also for FKTN (NM_001079802)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Fukutin was used as an immunogen.
Clone NameEPR7913 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IHC Suggested DilutionsICC/IF: 1:250 - 1:500; WB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens fukutin (FKTN), transcript variant 1
Alternative NameCMD1X; FCMD; LGMD2M; MDDGA4; MDDGB4; MDDGC4
Database LinkNP_001073270
FunctionFukutin is a putative transmembrane protein that is localized to the cis-Golgi compartment, where it may be involved in the glycosylation of alpha-dystroglycan in skeletal muscle. It is thought to be a glycosyltransferase and could play a role in brain development. Defects in Fukutin are a cause of Fukuyama-type congenital muscular dystrophy (FCMD), Walker-Warburg syndrome (WWS), limb-girdle muscular dystrophy type 2M (LGMD2M), and dilated cardiomyopathy type 1X (CMD1X) (1).
Related Pathway

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WB Image
Western blot - Anti-Fukutin antibody [EPR7913]; All lanes : Anti-Fukutin antibody [EPR7913] at 1/1000 dilution.Lane 1 : HeLa lysate.Lane 2 : A549 lysate.Lane 3 : Fetal heart lysate.Lane 4 : BxPC-3 lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 53 kDa.
Assay Image
Other-Anti-Fukutin antibody [EPR7913](TA310490); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Fukutin antibody [EPR7913]; Immunohistochemical analysis of paraffin-embedded Human kidney tissue labelling Fukutin with TA310490 at 1/100 dilution.

 

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