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Home Antibody All anti-FKBP6 antibodies

Anti-FKBP6 Antibody EPR3674

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307348
  • Rabbit monoclonal antibody against FKBP6(clone EPR3674)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC418553) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for FKBP6 (NM_003602)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the C-terminus in human FKBP6 was used as an immunogen.
Clone NameEPR3674 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsFC: 1 : 10 -100, IHC: 1 : 100 -250, WB: 1:1,000 - 10,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens FK506 binding protein 6, 36kDa (FKBP6), transcript variant 1
Alternative NameFKBP36
Database LinkNP_003593
FunctionFK506 binding protein 6 (FKBP6) is a cellular receptor for the immunosuppressants FK506 and rapamycin in the immunophilin FKBP family (1). FKBP’s are involved in several biochemical processes including protein folding, receptor signaling, protein trafficking and transcription (2). It forms a complex as FKBP-FK506 to competitively bind to and inhibit the Calcium- and calmodulin-dependent phosphatase calcineurin (3). FKBP6 plays a role in sex-specific fertility as a component of the synaptonemal complex, which is essential for chromosome pairing and meiotic division (4). A genetic deletion in FKBP6 is associated with Williams-Beuren syndrome (WBS), a neurodevelopmental disorder (5).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - FKBP6 antibody [EPR3674]; All lanes : Anti-FKBP6 antibody [EPR3674] at 1/1000 dilution.Lane 1 : Molt-4 cell lysate.Lane 2 : SAOS-2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit antibody at 1/2000 dilution.Predicted band size : 37 kDa.Observed band size : 38 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - FKBP6 antibody [EPR3674]; Ab92475 at 1/100 dilution staining FKBP6 in paraffin-embedded Human tonsil tissue, by immunohistochemistry.

 

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