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Home Antibody All anti-FKBP4 antibodies

Anti-FKBP4 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308638
  • Rabbit Polyclonal antibody to FKBP52 (FK506 binding protein 4, 59kDa)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419585) , 20ug Explanation
100ul 325 3-7 Days
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WB(3)
IF(1)
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Also for FKBP4 (NM_002014)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 207 of FKBP52 (Uniprot ID#Q02790)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.99mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 52kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens FK506 binding protein 4, 59kDa (FKBP4)
Alternative NameFKBP51; FKBP52; FKBP59; HBI; Hsp56; p52; PPIase
Database LinkNP_002005
Entrez Gene 2288 Human
Entrez Gene 14228 Mouse
FunctionThe protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It has high structural and functional similarity to FK506-binding protein 1A (FKBP1A), but unlike FKBP1A, this protein does not have immunosuppressant activity when complexed with FK506. It interacts with interferon regulatory factor-4 and plays an important role in immunoregulatory gene expression in B and T lymphocytes. This encoded protein is known to associate with phytanoyl-CoA alpha-hydroxylase. It can also associate with two heat shock proteins (hsp90 and hsp70) and thus may play a role in the intracellular trafficking of hetero-oligomeric forms of the steroid hormone receptors. This protein correlates strongly with adeno-associated virus type 2 vectors (AAV) resulting in a significant increase in AAV-mediated transgene expression in human cell lines. Thus this encoded protein is thought to have important implications for the optimal use of AAV vectors in human gene therapy. The human genome contains several non-transcribed pseudogenes similar to this gene. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
FKBP4 antibody detects FKBP4 protein by Western blot analysis. A. 30 ug Rat2 whole cell lysate/extract. 10 % SDS-PAGE. FKBP4 antibody (TA308638) dilution: 1:1000
WB Image
FKBP4 antibody detects FKBP4 protein by Western blot analysis. A. 30 ug 293T whole cell lysate/extract. B. 30 ug A431 whole cell lysate/extract. C. 30 ug HeLa whole cell lysate/extract. D. 30 ug HepG2 whole cell lysate/extract. E. 30 ug A375 whole cell ly
WB Image
FKBP4 antibody detects FKBP4 protein by Western blot analysis. A. 30 ug GL261 whole cell lysate/extract. B. 30 ug C8D30 whole cell lysate/extract. 10 % SDS-PAGE. FKBP4 antibody (TA308638) dilution: 1:1000
IF Image
Immunofluorescence analysis of paraformaldehyde-fixed A431, using FKBP52(TA308638) antibody at 1:200 dilution.

 

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